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Africa has proved vaccines work. In this opinion article, three high-profile participants in African healthcare debates argue that the continent's next challenge is whether Africa can transform immunisation into a strategic health system and economic asset rather than a donor-dependent programme. 

  • Governments are under growing pressure to finance immunisation domestically, expand local vaccine manufacturing and strengthen health systems as traditional donor funding becomes less predictable. How countries respond will shape not only public health outcomes but also the continent's broader health economy.

  • The authors argue that vaccines should no longer be viewed solely as a public health intervention. They contend that sustained investment in immunisation strengthens human capital, supports economic productivity and builds more resilient health systems, making vaccines one of Africa's highest-return long-term investments.

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