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We review the content for the past year with the three biggest stories in climate-health. The first counters long regulatory wait for clinical trials approval for faster vaccine manufacturing during pandemics. The second is a one of a kind investment by the Africa CDC in pharmaceutical companies to improve local manufacturing. The third is the launch of the the first coordinated climate-health fund at COP 30.

Treezer Michelle Atieno - Editor

When the next pandemic hits, induced by climate change or otherwise, Africa should no longer have to wait 1.5 years for vaccine trials to clear paperwork. A new partnership between The Coalition for Epidemic Preparedness Innovations and the WHO-led clinical trials institution in October will enable regulators to make multi-country approvals in as little as 15 days. 

  • African researchers and manufacturers currently face long regulatory waits that slow vaccine development. The standard approval timeline for multi-country clinical trials is between six and 18 months. 

  • According to the Africa CDC, climate change is making future pandemics more likely due to the increasing frequency, geographic spread, vulnerability and severity of infectious diseases.

  • Our take: Africa’s dependence on imported pharmaceutical products undermines access to essential medicines, making local health systems vulnerable in times of crisis…Read more (2 min)

In September, the Africa CDC started rolling out $3.2 billion in financing to boost African pharmaceutical and vaccine production. The plan is designed to tackle the continent’s heavy reliance on imports, which is currently at 99%. The new funding will support local manufacturers who can meet international quality standards.

  • Afreximbank has pledged $2 billion in financing, while Gavi’s African Vaccine Manufacturing Accelerator (AVMA) will provide $1.2 billion in grants to support the project. To qualify, companies must secure World Health Organization pre-qualification.

  • Local pharmaceutical manufacturing strengthens climate health by securing medicine supplies during climate-driven disruptions, cutting import emissions, and building resilient health systems to address rising heat, disease and food insecurity risks.

  • Our take: Local pharmaceutical manufacturing in Africa is a climate resilience strategy…Read more (2 min)

In November, more than 35 leading global health philanthropies launched the Climate and Health Funders Coalition and committed an initial $300 million for climate-health. The Coalition’s inaugural funding effort, announced at COP30 in Brazil, supports climate-health and the implementation of the Belém Health Action Plan.

  • This is the first time that a coalition of global health philanthropies is investing this amount directly in climate-health and the first formation of a joint fund for climate-health. The partners include the Gates Foundation, Rockefeller Foundation, Bloomberg Philanthropies, Wellcome and more.

  • The partners will agree on annual contributions, but the focus for the first $300 million will be to accelerate solutions, innovations, policies and research on extreme heat, air pollution and climate-sensitive infectious diseases in Africa and other continents.   

  • Our take: The fund’s early priorities like air pollution and infectious diseases align with the most urgent climate-linked health burdens in Africa…Read more (2 min)

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